On the other hand, ∼40% PC3 cells were ALDH+ (Figure 8A; Supplementary Figure 8A) and purified ALDH+ PC3 cells showed much higher clonal (Figure 8D), sphere-formation (Figure 8E), and tumor-regeneration (Table 1) capacities than the corresponding ALDH− PC3 cells. The gene discussed is LDHA; the disease is neoplasm.