AR and posterior cortical atrophy: We have shown preliminary evidence that 3 LNCaP sublines representing 3 subtypes of PCa cells, i.e., AR+PSA+ (regular LNCaP), AR+PSA− (LNCaP-abl) and AR−PSA− (LNCaP-CDSS and LNCaP-MDV) exhibit differential responses to antiandrogens, chemodrugs, and targeted therapeutics.