KLK3 and posterior cortical atrophy: To explore potential differences between subtypes of PCa cells in response to therapeutics, we performed a preliminary study in three types of LNCaP cells (Figure 2F), i.e., AR+PSA+ wild-type LNCaP, AR+PSA− LNCaP-abl [25], and AR−PSA− LNCaP-CDSS and LNCaP-MDV cells, the two castration-resistant LNCaP sublines we recently established (Rycaj et al., manuscript submitted).