Similarly, Suda et al., using a mouse model, found that the AT1R-blocker telmisartan prevented alveolar-bone loss in mice heterozygous for FBN1 (Marfan syndrome) infected with P. gingivalis for 14 d when compared to control mice which were heterozygous for FBN1 without P. gingivalis infection [39]. This evidence concerns the gene AGTR1 and Marfan syndrome.