In particular, the mRNA expression for the AT1R in gingiva was not different among the healthy, gingivitis and periodontitis groups 1.6 (±1.0), 1.4 (±1.7) and 0.9 (±1.7) respectively; likewise the mRNA expression for the MasR was not different among the gingiva from the healthy group, gingivitis group and periodontitis group, 1.0 (±1.5), 1.0 (±2.1) and 0.6 (±1.6) respectively (Fig 2A). This evidence concerns the gene AGTR1 and periodontitis.