Similarly, liquid colony formation assay showed that PPARγ ligand treatments inhibited clonogenecity of HBECs expressing wt-PPARγ and other lung cancer cell lines such as calu6 and H2347 expressing endogenouse PPARγ, but not of the one with SUMO-PPARγ (Fig 7B and 7C). Here, PPARG is linked to lung carcinoma.