PPARG and type 2 diabetes mellitus: Since the PPARγ has been relatively well-studied amongst other NRs in diverse physiological functions (e.g., adipocyte differentiation, inflammation control) and its ligand TZDs available in the clinic of type II diabetes, we next decided to investigate the molecular study of PPARγ, as a proof-of-concept, out of the 48 NRs in the molecular pathogenesis of lung cancer [11, 34, 35].