IFI6 and infection: IFI6 up-regulated in HUVECs after infection with DENV2 for 48 hrs by GeneChip hybridization and analysis (Fig 1, panel a, top), and mRNA expression of IFI6 in primary HUVECs isolated from human umbilical veins was markedly up-regulated after 48 hrs post DENV2 infection(Fig 1, panel a, below).