In order to analyze the effects of CITED4, in vitro, the CRC cell line SW480, derived initially from a 50-year-old male with Dukes stage B CRC (Leibovitz et al. 1976), was used to generate both a CITED4-overexpressing and two CITED4 shRNA-mediated knockdown permanent cell lines. Here, CITED4 is linked to colorectal carcinoma.