ALDH1A1 and neoplasm: Tumor analysis revealed that sh-Aldh1a1 cells produced tumors of similar weight (Fig. 5a) and volume (Fig. 5b) than those originated from wild type B16F10 cells, indicating that, at least in our experimental conditions using immunocompetent recipient mice, Aldh1a1 depletion alone was not enough to affect melanoma primary tumorigenesis.