A2M and tuberculosis: In our study, proteome analysis of malnourished individuals with a) active TB, b) latent TB infection, c) with no clinical or bacteriological signs of active or latent TB and healthy controls identified three most differentially expressed proteins namely; Alpha 2-Macroglobulin (A-2-M), Sero-transferrin and Haptoglobin in the serum samples from the four study groups.