Serum AST and age were independent predictive parameters in chronic hepatitis C. Next, we performed logistic Cox regression analysis on all HIV-positive patients using “HCV infection” as an additional categorical covariate (Table 5), which confirmed HLA-B*57 (p = 0.002), gamma-glutamyltranspeptidase (p = 0.001), bilirubin (p = 0.007), and CD4 count (p = 0.037) as significant independent predictors of mortality. This evidence concerns the gene GGTLC1 and chronic hepatitis C virus infection.