In this regard, of interest is a small study of patients during their first hospitalisation with a schizophrenia spectrum disorder (schizophrenia, schizoaffective disorder or schizophreniform disorder) that reported no difference in levels of SELENBP1 mRNA in blood compared with controls.33 Significantly, that study involved patients in their first admission, whereas other studies utilised patients with an established diagnosis of schizophrenia, suggesting that differences in SELENBP1 expression may depend on disease state. Here, SELENBP1 is linked to schizoaffective disorder.