We also addressed the extent of changes in cortical SELENBP1 expression by measuring mRNA levels in multiple cortical regions, determined whether a two-marker haplotype of SELENBP1, previously shown to be nominally associated with risk for schizophrenia (rs10788804, allele A; and rs2800953, allele A or G),9 influenced brain SELENBP1 expression, and whether changes in SELENBP1 mRNA translated to changes in protein levels. Here, SELENBP1 is linked to schizophrenia.