Figure 5 shows the network context of the two pathways Acute Phase Response Signaling and HIF1 Signaling and the possible role of hsa-mir-181b-2 using IPA software.  Figure 6 shows hsa-let-7c and target genes in Human Embryonic Stem Cell Pluripotency, Estrogen-Dependent Breast Cancer Signaling, and Molecular Mechanism of Cancer, according to IPA software. This evidence concerns the gene HIF1A and cancer.