ALB and type 1 diabetes mellitus: The Renin-Angiotensin Study (RASS) was a five-year multicenter, randomized, double-blind, placebo-controlled trial comparing enalapril and losartan with placebo on early renal structural changes from diabetic nephropathy in T1DM patients without hypertension, albumin excretion rate above 20 mg/min and a glomerular filtration over 90/mL/min/1.73 m2.