Complications of malignancy in personal histories and/or in coexisting/underlying disorders were recognized in three (5%) of the 60 elderly AE patients: rectal cancer and prostatic carcinoma in one patient with IgE-allergic AE, prostate carcinoma in one patient with indeterminate-allergic AE, and stomach cancer in one patient with non-IgE-allergic AE. Here, IGHE is linked to rectal cancer.