SLC5A2 and Hypoglycemia: Metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide 1 (GLP-1) mimetics and sodium glucose cotransporter-2 (SGLT2) inhibitors do not increase the risk of hypoglycemia when used without sulfonylureas or insulin [30,34,40].