BECN1 and ovarian serous tumor: In order to assess the relationship between BECN1 copy-number and expression, we interrogated level 3 array comparative genomic hybridization (aCGH) and RPPA data generated by TCGA from a large number of high-grade serous ovarian tumors (91 % of which are from metastatic, stage III-IV disease; Additional file 2: Table S2).