CYP3A4 and neoplasm: In addition, we measured the expression of a number of other genes in the tumours including nuclear receptors (VDR, RXRα, SXR, ER α and β), cytochrome P450 enzyme (CYP3A4), proliferation marker (MCM2, CDC6, KI67), differentiation marker (sucrase isomaltase) and angiogenesis marker (CD31).