Of those, the serum levels of alanine aminotransferase (ALT) and total bilirubin (TBIL) were obviously higher in cases of HCC, LC and CHB compared with the healthy controls (P < 0.05), whereas the albumin (ALB) and platelet (PLT) levels were higher in the healthy controls (P < 0.05). This evidence concerns the gene ALB and laryngotracheoesophageal cleft.