Covariates in the multivariate model included age, sex, duration of dialysis, a history of diabetes, hypertension, coronary artery disease and cerebrovascular disease, systolic and diastolic blood pressure, body mass index, baPWV, albumin, fasting glucose, triglyceride, total cholesterol, hemoglobin, creatinine, CaXP product, iPTH, uric acid, Kt/V and ultrafiltration percent. The gene discussed is ALB; the disease is cerebrovascular disorder.