REN and familial dilated cardiomyopathy: Various vasoactive drugs, such as renin inhibitor, angiotensin convertase enzyme inhibitor (ACEI), angiotensin II receptor blocker (ARB), beta adreno-receptor blockers and calcium channel blockers, have been used in the management of hypertension, CAD and HF and have been found to be beneficial for patients with DCM [46,47].