A group of three adaptor proteins, SLP-76, Grb2, and Nck, dynamically connected central signaling to the lamellum while retaining some central enrichment to a variable extent, as again corroborated in DO11.10 T cell:A20 B cell lymphoma cell conjugates (S2O and S2Q Fig). Here, LCP2 is linked to B-cell non-Hodgkin lymphoma.