The presence of scoliosis was significantly associated with IL-4 (r = 0.424, P < 0.0001), IFN-γ (r = −0.458, P < 0.0001), IL-12p70 (r = −0.327, P = 0.0029), IL-4/IFN-γ ratio (r = 0.491, P < 0.0001), IL-5/IFN-γ ratio (r = 0.442, P = 0.0001), and IL-6/IFN-γ ratio (r = 0.429, P = 0.0001). The gene discussed is IL5; the disease is scoliosis.