Girardelli et al. [8] et al. hypothesized a role for NLRP1 inflammasome in the context of mesothelioma on the basis of NLRP1 lung expression (alveolar macrophages and epithelial cells), a location where this innate immune protein could act as sensor of asbestos fibres. This evidence concerns the gene NLRP1 and mesothelioma.