Therefore, results in LIC evaluation differ and must be compared with caution: here, one has to mention adult versus pediatric B-ALLs, different immunophenotypes (common ALL, pre-B-ALL, pro-B-ALL, etc.), different genotypes, and mutational status (e.g., BCR-ABL positive versus negative, MLL rearrangement positive or negative) as also described in Table 1. Here, KMT2A is linked to acute lymphoblastic leukemia.