The association of tumor size with a different TNRC6B variant (rs12484776) in RFTS (Edwards et al., 2013a), albeit moderately (P = 0.024), supports a candidate status for this gene because the observed association with a different variant in the same gene in RFTS reduces the possibility of biased results for rs138039 and rs139909 in NIEHS-UFS (not tested in RFTS). Here, TNRC6B is linked to neoplasm.