The TNRC6 paralogs encode members of the GW182 protein family that are essential components of the miRNA pathway (Yao et al., 2012), which has been implicated in the pathogenesis of uterine fibroids (Marsh et al., 2008; Wei and Soteropoulos, 2008). The gene discussed is TNRC6A; the disease is uterine corpus leiomyoma.