MUC16 and neoplasm: Even in the platinum-resistant HGSC in vitro carboplatin treatment targeted the CA125-positive cells and spared the CA125-negative population (Fig. 8a), but co-therapy with birinapant and carboplatin could eliminate all tumour cells in the specimen where high levels of cIAP were present in the CA125-negative cells (Fig. 8b and Supplementary Data 1).