Among these shared traits are reduced serum IGF-1 levels [6], reduced cellular senescence in white adipose tissue [10], decreased mTOR activity [34], protection from musculoskeletal frailty with better retention of strength, balance, and motor coordination in old age [9], reduced rates and delayed occurrence of cancer [15], and enhanced glucose homeostasis with reduced levels of circulating insulin [4]. This evidence concerns the gene MTOR and cancer.