Glucose clearance during an OGTT at week 18 was not different between B6-WT and B6-Tg(Zfp69) mice (Fig. 2a), but the insulin concentration was significantly increased in B6-Tg(Zfp69) mice (Fig. 2b), suggesting that Zfp69 overexpression causes mild insulin resistance. Here, INS is linked to Insulin resistance.