KLK6 and neoplasm: However, when only gender and ECOG performance scores were included as covariates in the multivariable analysis, scores for KLK6-IR and KLK9 % tumor core stained, retained their significant association with survival (HR = 1.15, CI = 1.01–1.30, P = 0.03 and HR = 2.13, CI = 1.12–4.05, P = 0.021, respectively; Table 3).