Considering the present Western blot data, these two mechanisms may contribute differently to the pathogenesis of individual IIP subtypes; the αCTF mechanism profoundly impacts AIP, f-NSIP, and COP and relatively mildly impacts UIP, while the full-length CADM1 mechanism acts particularly on f-NSIP. The gene discussed is AIP; the disease is idiopathic pulmonary fibrosis.