CD14+HLA-DRlow/− cells are increased in several solid tumors, including metastatic melanoma,27 hepatocellular carcinoma,28 squamous cell carcinoma of the head and neck,29 glioblastoma,30 prostate cancer31 and chronic lymphocytic leukemia.32, 33 Our previous study observed14 that the numbers of CD14+HLA-DRlow/− monocytes increased in relapsed B-cell NHL patients. The gene discussed is CD14; the disease is head and neck squamous cell carcinoma.