At all time points after injection, the serum SOD activities in sSCP1 and SCP groups were significantly higher than those in VC and BC groups (P<0.05), in sSCP1 group were the highest, on D7–D14 significantly higher than those in SCP group (P<0.05) and on D21–D28 numerically higher than those in SCP group (P>0.05). This evidence concerns the gene SOD1 and breast cancer.