AGT and heart failure: The contribution of Ang II to the pathogenesis of hypertension, cardiac hypertrophy and heart failure, alongside with Ang II role in body fluids homeostasis [9, 10], and the previously published existence of Ang II receptors in AEC II[11], led us to investigate the role of Ang II on AFC in AEC II, and the molecular mechanisms by which Ang II exerts its effect on AFC.