PTH and endocrine system disorder: Primary hyperparathyroidism (PHPT) occurs due to the overproduction of parathyroid hormone (PTH) in the body and is one of the most common endocrine disorders diagnosed throughout the world.2 Excess secretion of PTH results in hypercalcaemia and can be attributable to neurological, psychiatric, or muscular problems and brittle bones3; however, 50% or more of newly diagnosed cases of PHPT may be completely asymptomatic, and are detected by commonly used multi-channel blood screening tests.2,4 In the majority of cases (80–85%), PHPT is caused by one or more parathyroid adenoma(s) (PAs).