On the other hand the serum levels of ADIPOQ, CXCL9, PECAM-1, Prolactin, sVEGFR-1 and sVEGFR-2 in the T2D-HCC patients were higher than those of patients with only T2D while they were similar to those of HCC patients, confirming that these proteins are specific for the cancer presence. This evidence concerns the gene PRL and type 2 diabetes mellitus.