CDKN1A and systemic lupus erythematosus: Interestingly, the miRNAs that we found deregulated in SLE memory B cells are mainly predicted to target genes previously associated with SLE pathogenesis or B cell biology, and a list of seven genes (CDKN1A, CSF1, IFNG, JUN, MMP9, NF-κB1, and P53) showed significant enrichment in inflammatory disease and response, renal inflammation, and renal nephritis canonical pathways.