CD4 and HIV infectious disease: As expected, higher baseline CD4 count was associated with higher CD4 cell gains (estimate = 0.94 per cell, 95% CI [0.90, 0.98] cells/mm3, p<0.001) and longer HIV infection duration at cART initiation was associated with lower CD4 cell counts following cART initiation (estimate = -0.08 per week, 95% CI [-0.11, -0.05] cells/mm3, p<0.001).