SERPINA1 and Insulin resistance: This region contained 13 genes, including GSC (a transcription factor that defines neural-crest cell-fate specification and contributes to dorsal—ventral patterning [26]), RETNLB (resistin-like beta, associated with insulin resistance), PPP4R4 (Protein Phosphatase 4, Regulatory Subunit 4, a putative regulatory subunit of serine/threonine-protein phosphatase 4) and 10 genes in the SERPINA family (Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase), members 1,2,3–6,9–13).