Also, treatment of adhered NPC cultures with prostratin induced a 2.5-fold increase in the percentage of Ki67+ cells, which was reduced by pretreatment with the PKC inhibitor G06850 even below control levels (Figure 2G-H), confirming that prostratin-induced activation of PKC was responsible for this rise in the number of cycling cells. Here, PRRT2 is linked to nasopharyngeal carcinoma.