In 225 patients with GCA and 1378 controls in the novel UK cohort, a susceptibility effect of HLA-DRB1*04 carriage was confirmed (odds ratio (OR) 2.69, 95 % confidence interval (CI) 2.02 to 3.58, P = 1.5×10−11) (Table 3). Here, HLA-DRB1 is linked to temporal arteritis.