HLA-DRB1 and temporal arteritis: Under-representation of HLA-DRB1*01 in GCA patients from Rochester, Minnesota, led to a suggestion that the risk of GCA may be due to a DRYF motif at positions 28–31 in the second hypervariable region (HVR2) of MHC class II [12], but a Spanish study failed to replicate this finding [13].