Fibromyalgia has been genetically linked to chromosome region 17p11.2-q11.2 2, which encodes some proteins also involved in neuropathic pain, such as Erk5 9, nitric oxide synthase 2 (NOS2) 10 and transient receptor potential vanilloid 2(TRPV2) 11. This evidence concerns the gene NOS2 and fibromyalgia.