Ionotropic GABAA receptors are heteropentameric assemblies of 5 subunits, which are chosen out of 19 identified subunits in mammals: α1–6, β1–3, γ1–3, δ, ε, ρ1–3, θ and π [9] and which are unlinked to the FXS causative FMR1 gene. The gene discussed is FMR1; the disease is fragile X syndrome.