MGMT and neoplasm: A consecutive pathologic electron microscopy showed an atypical sparsely granulated corticotroph tumour, with an MIB-1 index >5% (Figures 1 and 2), very low activity of O6-methylguanine DNA methyltransferase (MGMT) in tumour cells (Figure 3), and positive receptor SSRT 2A (weak cytoplasmic) reaction.