The role of TNF-α in autophagy is also supported by studies on M. tuberculosis, since reactivation of tuberculosis associated with anti-TNF-α treatments (infliximab, adalimumab, certolizumab pegol, and etanercept) is suspected to, at least partially, depend on suppression of the antibacterial autophagic process [63, 64]. The gene discussed is TNF; the disease is tuberculosis.