Alpha-synuclein aggregates in Parkinson’s disease (Spillantini et al., 1998b) and it has been reported to interact with tau (Giasson et al., 2003; Goris et al., 2007; Satake et al., 2009; Simón-Sánchez et al., 2009). The gene discussed is SNCA; the disease is Parkinson disease.