NEK2 and cancer: Given that Nek2A activity has been found to be elevated in many human tumors (Cappello et al., 2014; Hayward and Fry, 2006), it will be of great interest to examine the relevance of these two proteins by comparing the levels of Cep85 in primary cell lines with those in related cancer lines, as well as the levels in normal tissues with those in tumor samples, especially samples with high Nek2A activity.