STMN1 and lung cancer: However, on the basis of information about the correlation between the expression of STMN1 and efficacy of therapies based on the taxane or vinca alkaloids and that −2166T>C single nucleotide polymorphism (SNP) is located within or close to the putative transcriptional control region [14], it can be concluded that there exists potential predictive importance of this kind of genetic change (polymorphisms) in lung cancer patients.