Due to increased risk of breast cancer development, miR-132 levels may be lowered, and as a result, further nocturnal exposure to light would not only increase deregulation of the circadian clock due to the inhibition of homeostasis induced by miR-132, but also cause lowered oncostatic activity through increased transcriptional inhibition of the Period genes by PAIP2A and BTG2. The gene discussed is CLOCK; the disease is breast carcinoma.