SNCA and Parkinson disease: AsLK6 is homologue of human Mnk2a, we further identified that Mnk2a can phosphorylate α-synuclein by the ERK signal pathway, and leads to α-synuclein inclusion (Lewy body) agglomeration in human and mouse neurons, showing that Mnk2a may play a pivotal role in the formation of Parkinson’s disease.