SNCA and Parkinson disease: The results indicated that almost half of the α-synuclein transgenic flies over-expression of lk6 died at the age of 20 (w; elav-gal4/+; UAS-synuclein/UAS-Lk6), while 80% of the control flies (w; elav-gal4/+;+/+) and 70% of the PD flies (w; elav-gal4/+; UAS-synuclein/+) are alive (Fig. 4A).