Kaplan-Meier-survival analyses revealed that lower expression of cytoplasmic Pak4 (P = 0.026), but not Pak1, nuclear and cytoplasmic p-Pak2, nuclear Pak4, nuclear and cytoplasmic p-Pak4, resulted in a poorer survival in endometrial cancer patients (Figs 1D, 2C, 3C and 4C). This evidence concerns the gene PAK1 and endometrial cancer.