Antibodies against contactin-1, neurofascin and gliomedin have been reported to be present in 2–10% of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and are supposed to be associated with a typical clinical phenotype of acute onset severe sensorimotor neuropathy and tremor [4,5,6,7]. Here, NFASC is linked to chronic inflammatory demyelinating polyradiculoneuropathy.