Positive; patients with higher stage or Gleason Score prostate cancer had higher CD68+ TAM counts. Patients with PSA failure had significantly higher TAM counts than those without. Recurrence-free survival was significantly lower in patients with high TAM counts than those with low TAM counts. TAM count was determined to be a significant prognostic factor in addition to PSA, Gleason Score, extraprostatic extension, lymph node metastasis, and distant metastasis. Here, CD68 is linked to prostate cancer.